Adaptogens are typically defined as synthetic or plant-based chemicals that directly impact the body. Adaptogens can be found in multiple natural foods. However, if you’re unaware of foods rich in adaptogens, you should take adaptogenic supplements. Adaptogens help the body recover from short and long-term stresses. 

If you eat fewer fruits and veggies, you should also consider eating fruit and vegetable supplements. Choosing an adaptogenic supplement without doing research can be tricky. So, we researched for you! 

Top 10 Adaptogenic Anxiety & Stress Supplements

Best Value: Integrative Therapeutics HPA Adapt

Best For Fatigue: Metagenics Adreset Supplement 

Best Liquid Supplement: Sun Eleuthero Extract Natural Supplement

Best With Mushrooms: Enveed Superfood Adaptogens

Best Daytime Supplement: Gaia PRO Daytime HPA 

Best For Sleeping: Livingood Daily De-Stress 

Best With Saffron: Dr. Amy Myers ZenAdapt – Adaptogen Supplement

Best Mood Lifter: Meccene Adaptogens Supplement

Best Powdered Supplement: Four Sigmatic Adaptogen Blend Mix

Best Vegan: Perfect Supplements Perfect Rhodiola Rosea

Best Value: Integrative Therapeutics HPA Adapt

integrative Adaptogenic Anxiety & Stress Supplements

Using a herbal blend, this dietary supplement optimizes the HPA axis function. Resistance against stress is supported using ingredients like Rhodiola root extract, ashwagandha, maca, and eleuthero root extract. These herbs work to regulate the stress hormonal system and reduce overall stress. 

Integrative Therapeutics HPA Adapt induces calmness while improving cognitive functioning. This supplement is suitable for all since it is gluten-free, dairy-free, soy-free, and contains no artificial colors or flavors. Being highly reasonable, this supplement only costs $0.33 per capsule. While the recommended dosage is 4 capsules daily, you can adjust it accordingly. 

Best For Fatigue: Metagenics Adreset Supplement 

metagenics adreset Adaptogenic Anxiety & Stress Supplements

This supplement is designed for people who feel fatigued and weak due to stress. Adaptogens are scientifically proven to build resistance and stamina in people facing stress and reduce its implications. Using ingredients like cordyceps, Rhodiola, and ginseng, the Metagenics Adreset supplement is perfect for individuals who want to adapt to stressful surroundings. 

Day-to-day stress can harm health, so using adaptogens to build resilience against it is necessary. You should consume 2 capsules per day. This supplement is priced at $0.61 per capsule and is non-GMO, gluten-free, and vegetarian-friendly.

Best Liquid Supplement: Sun Eleuthero Extract Natural Supplement

sun eleuthero Adaptogenic Anxiety & Stress Supplements

A liquid supplement can be easier to consume than capsules or tablets. This is a nootropic tranquility with a blend of natural adaptogens to help people cope with physical and mental stress. With pulverized chlorella, you will feel rejuvenated and energized as it focuses on boosting athletic energy and metabolism. 

The eleuthero extract used in this supplement is grown in rich soils in Asia and is free from chemicals or pesticides. Just 30 ml of this supplement daily will make you feel less anxious and more energetic.  This liquid is slightly expensive, costing $5.07/ounce, but it is magic. 

Best With Mushrooms: Enveed Superfood Adaptogens

Enveed Superfood Adaptogens supplement is vegan, non-GMO, and gluten-free. Each capsule is easy to swallow and provides energy while helping you cope with stress. You’ll feel better and less stressed out with this herbal adaptogen supplement. Using maca, ashwagandha, gotu kola, and holy basil, this blend of natural ingredients provides immune support to the body. 

Containing numerous antioxidants, this supplement will reduce inflammation, stress and provide mental clarity while boosting energy. These supplements cost $0.40/capsule and must be used twice daily. 

Best Daytime Supplement: Gaia PRO Daytime HPA 

An increase in cortisol levels induces stress, and this supplement controls healthy cortisol levels in the system. Asian ginseng, one of the main ingredients, supports a healthy adrenal system and relieves nervousness. You’ll stay active through the day with Gaia PRO Daytime HPA. 

The ingredients in this herbal supplement include holy basil, oats, Siberian Rhodiola, Schisandra, and ashwagandha. The daily recommended dosage is 2 capsules a day. This supplement costs $0.58/capsule and comes as liquid phyto-capsules. 

Best For Sleeping: Livingood Daily De-Stress 

livingood daily Adaptogenic Anxiety & Stress Supplements

Livingood Daily De-Stress supplement promotes healthy sleeping patterns by controlling cortisol levels, hypothalamic and pituitary function, and dopamine production. This boosts immunity and provides energy. This unique blend of herbs contains ashwagandha, reishi mushroom, Rhodiola, and ginseng. 

These ingredients keep you stress-free without any brain fog throughout the day. These capsules are vegan, corn-free, glyphosate-free, fillers-free, and gluten-free. You need to consume 2 capsules with meals during the day or night. Each capsule costs $0.78.

Best With Saffron: Dr. Amy Myers ZenAdapt – Adaptogen Supplement

amy myers md Adaptogenic Anxiety & Stress Supplements

This supplement contains saffron which, while being the most expensive spice in the world, has numerous benefits. Dr. Amy Meyers MD ZenAdapt supplement also contains ashwagandha extract, Rhodiola extract, and Venetron extract. 

These ingredients make this supplement reliable and healthy without any implications. You need to take 2 capsules daily to promote a stress-free lifestyle. It is free of gluten, soy, GMOs, and yeast. This supplement costs $0.46/capsule. 

Best Mood Lifter: Mecene Adaptogens Supplement

Made with natural ingredients, Mecene Adaptogens Supplement helps restore sleep, relieves stress, improves mood, and boosts adrenal health. This multi-purpose adaptogen supplement is supposed to be taken twice a day with meals. This supplement reduces stress-induced fatigue by using schisandra, ashwagandha, holy basil, eleuthero extract, and Panax ginseng. It supports adrenal glands to maintain healthy cortisol levels so you can stay active and stress-free throughout the day. This supplement is priced at $0.36/capsule and is one of the cheapest adaptogen supplements. 

Best Powdered Supplement: Four Sigmatic Adaptogen Blend Mix

This supplement can be added to your favorite drink or baked goods. Easy to dissolve and use, the Four Sigmatic Adaptogen supplement comes in powdered form with special chaga and reishi mushrooms. These 2 mushroom extracts boost immune defense and calm the mind, keeping you stress-free. 

Using herbal ingredients, you can use this supplement anytime, even if you are following a vegan, keto, or paleo diet. Add one scoop to your coffee or tea, and you’re ready for the day. This supplement costs $9.26/ounce and is quite literally herbal magic. 

Best Vegan: Perfect Supplements Perfect Rhodiola Rosea

With 100% wildcrafted and freeze-dried Siberian Rhodiola root extract, the All Natural Perfect Rhodiola Rosea Supplement is meant to be taken twice daily. Not only does it reduce stress, it boosts mood, provides mental clarity, and also improves memory. 

This supplement is gluten-free, vegan, and non-GMO. If you’re looking for extra energy in your day, then start using this supplement. This supplement is only $0.42/capsule and is completely natural and free from side effects. 

Which Adaptogens Are Good For Health? 

Arctic Root

The arctic root, when taken alongside antidepressants, provides energy and boosts productivity. It also helps people recover quickly from illnesses such as the flu. 


This adaptogen is most beneficial for fighting exhaustion, fatigue, and low mental and physical activity. It can also help treat certain mental disorders. 


This herb is part of Ayurvedic treatment. Various clinical studies have revealed that ashwagandha helps reduce anxiety and stress.


Adaptogenic supplements are highly beneficial, especially if you face daily stress and work in strenuous surroundings. These adaptogenic supplements that we searched for you are herbal and have no side effects. Adding these to your regular diet will maintain cortisol levels in your body, promote sleep, boost energy, and improve your mood. 

You should also check for vitamin deficiency if your hands and feet feel cold. After going through these top 10 adaptogenic anxiety & stress supplements, you should opt for an adaptogenic supplement that suits your specific needs. 


Who should avoid adaptogens?

Adaptogens should be avoided by pregnant and breastfeeding women, diabetic patients, those with blood pressure and stomach issues, and those with autoimmune disorders. 

Do adaptogens affect hormones? 

Adaptogens are natural plant-based materials that regulate the hormonal system to control stress. They normalize the body processes that can become dysregulated. 

Are adaptogens harmful?

Adaptogens are safe to consume. While side effects are rare, they are possible. These side effects mainly include allergic reactions. 

Do adaptogens make you sleepy?

Adaptogens reduce cortisol levels in the body and calm down the nervous system. Hence, they help you fall asleep quickly and for a longer time.