No one likes being depressed! It’s the constant feeling of hopelessness, sadness, or disinterest that negatively impacts our lifestyle. To find relief from this disease, several brands have launched depression supplements and we’re going to take a look at the top five supplements to increase serotonin and dopamine.

You can also check out our article on the top 10 probiotic supplements for a healthy gut but, for now, our focus remains on helping folks tackle depression worldwide. Our guide today will provide a deeper understanding of five depression supplements, their ingredients, benefits, and cost.

5 Supplements to Increase Serotonin and Dopamine

Best Overall: St. John’s Wort

Best Budget Option: Omega-3 Fatty Acids

The Best for Vegans: Saffron Extract

Best for Older Adults: SAMe (S-adenosylmethionine)

The Best for Mild Depression: 5-HTP (5-Hydroxytryptophan)

Best Overall: St. John’s Wort

180-capsule bottle of Supplements To Increase Serotonin And Dopamine In USA

Company: Hypericum’s Heaven

Founder/CEO: Dr. Daisy Meadows

St.John’s Wort is a depression supplement made using 300mg of St. John’s Wort Extract. St. John’s Wort contains hypericin and hyperforin, compounds thought to increase the availability of the neurotransmitters serotonin, dopamine, and norepinephrine, which can boost mood and emotional resilience.

A 180-capsule bottle of St. John’s Wort is available for $13.

Best Budget Option: Omega-3 Fatty Acids

120 capsule bottle of Supplements To Increase Serotonin And Dopamine In USA

Company: OmegaLife

Founder/CEO: Richard Fishman

Omega-3 Fatty Acids are found in fish oil and have proven to be beneficial for brain health. They are a strong tool against depression, and this supplement contains over 1000mg of Omega-3 Fatty Acids. 

Omega-3 fatty acids are EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid). These are known to enhance brain function and mood. 

A bottle of 120 capsules can be purchased for around $15.

The Best for Vegans: Saffron Extract

60 capsule bottle of depression supplements

Company: Purely Plant

Founder/CEO: Ava Green

The best depression supplement for a vegan lifestyle is Saffron Extract by Pureply Plant! It contains 30mg of Saffron extract and is a precious spice as effective as certain antidepressants. 

The potential antidepressant effects of saffron are due to safranal and crocin, two compounds found in the spice. 

A 60-capsule bottle of Saffron Extract is available for approximately $40.

Best for Older Adults: SAMe (S-adenosylmethionine)

60-tablet bottle of serotonin supplement for men in 30s

Company: AgeWell Solutions

Founder/CEO: Dr. Johnathan Gray

SAMe is made in the body and takes care of key functions and hormones such as serotonin ( a mood stabilizer). As we age, our bodies natural production of SAMe can decrease. Adding AgeWell Solution’s SAMe supplements can help improve mood and alleviate depression, making it our top pick for older adults.

This supplement contains over 400mg of SAMe and helps produce and regulate hormones like serotonin. 

A 60-capsule bottle costs around $45.

The Best for Mild Depression: 5-HTP (5-Hydroxytryptophan)

120 capsule bottle of depression supplements for men in 30s

Company: MoodBoost

Founder/CEO: Dr. Sophia Lin

5-HTP by MoodBlast is one of the finest supplements in the market to combat depression. It contains over 100mg of 5-HTP (a naturally occurring amino acid and a precursor to the neurotransmitter serotonin).
5-HTP increases serotonin levels, which can reduce symptoms of depression. 

A 120-capsule bottle of this supplement is available for around $30.

Benefits of Supplements to Increase Serotonin and Dopamine

Now that you know all about the top five Supplements To Increase Serotonin And Dopamine, let’s talk about the benefits they can provide. These supplements can enhance mood, improve sleep quality, reduce feelings of anxiety, and support overall brain health.

St. John’s Wort, for instance, has shown effective results to standard antidepressants in treating mild to moderate depression. S-adenosylmethionine (SAMe) enhances the effects of antidepressants, while the B vitamins, particularly B6, B9 (folate), and B12, play vital roles in mental health and mood regulation.

Conclusion

That concludes our list of the top five Supplements To Increase Serotonin And Dopamine. If you enjoyed reading this, check out the top 5 oral supplements for constipation. In conclusion, dietary supplements may offer substantial benefits for those grappling with depression. 

They can provide an alternative treatment for those looking for a change from natural remedies. Start fighting your depression today with these!

FAQs

Can supplements cure depression? 

Supplements can help manage symptoms of depression, but they should not be viewed as a cure. It’s essential to consult with a healthcare provider for a comprehensive treatment approach.

Are there side effects to these supplements? 

Yes, potential side effects depend on the supplement and may include digestive upset, insomnia, and interaction with other medications.

How long do I need to take these supplements? 

The duration varies depending on the supplement and individual response. It can take a few weeks to notice any improvements.

Can I take these supplements with antidepressant medications? 

Some supplements may interact with antidepressant medications, potentially causing harmful effects. Always consult with a healthcare provider before combining supplements with other medications.

Does the FDA approve these supplements?

Dietary supplements do not require approval by the FDA for the treatment of depression. However, they are regulated as food products and must meet specific quality standards.

References:

https://pubmed.ncbi.nlm.nih.gov/12418499/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/